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Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq
Single-cell sequencing, which is used to detect clinically important tumor subpopulations, is necessary for understanding tumor heterogeneity. Here, we analyzed transcriptomic data obtained from 34 single cells from human lung adenocarcinoma (LADC) patient-derived xenografts (PDXs). To focus on the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549254/ https://www.ncbi.nlm.nih.gov/pubmed/26305796 http://dx.doi.org/10.1371/journal.pone.0135817 |