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Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq

Single-cell sequencing, which is used to detect clinically important tumor subpopulations, is necessary for understanding tumor heterogeneity. Here, we analyzed transcriptomic data obtained from 34 single cells from human lung adenocarcinoma (LADC) patient-derived xenografts (PDXs). To focus on the...

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Detalles Bibliográficos
Autores principales: Min, Jae-Woong, Kim, Woo Jin, Han, Jeong A., Jung, Yu-Jin, Kim, Kyu-Tae, Park, Woong-Yang, Lee, Hae-Ock, Choi, Sun Shim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549254/
https://www.ncbi.nlm.nih.gov/pubmed/26305796
http://dx.doi.org/10.1371/journal.pone.0135817