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Supporting Role for GTPase Rab27a in Hepatitis C Virus RNA Replication through a Novel miR-122-Mediated Effect

The small GTPase Rab27a has been shown to control membrane trafficking and microvesicle transport pathways, in particular the secretion of exosomes. In the liver, high expression of Rab27a correlates with the development of hepatocellular carcinoma. We discovered that low abundance of Rab27a resulte...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Chun, Hsieh, Chung-Han, Sarnow, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549268/
https://www.ncbi.nlm.nih.gov/pubmed/26305877
http://dx.doi.org/10.1371/journal.ppat.1005116