Distinct OGT-Binding Sites Promote HCF-1 Cleavage

Human HCF-1 (also referred to as HCFC-1) is a transcriptional co-regulator that undergoes a complex maturation process involving extensive O-GlcNAcylation and site-specific proteolysis. HCF-1 proteolysis results in two active, noncovalently associated HCF-1(N) and HCF-1(C) subunits that regulate dis...

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Detalles Bibliográficos
Autores principales: Bhuiyan, Tanja, Waridel, Patrice, Kapuria, Vaibhav, Zoete, Vincent, Herr, Winship
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549301/
https://www.ncbi.nlm.nih.gov/pubmed/26305326
http://dx.doi.org/10.1371/journal.pone.0136636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549301/
https://www.ncbi.nlm.nih.gov/pubmed/26305326
http://dx.doi.org/10.1371/journal.pone.0136636

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