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Distinct OGT-Binding Sites Promote HCF-1 Cleavage
Human HCF-1 (also referred to as HCFC-1) is a transcriptional co-regulator that undergoes a complex maturation process involving extensive O-GlcNAcylation and site-specific proteolysis. HCF-1 proteolysis results in two active, noncovalently associated HCF-1(N) and HCF-1(C) subunits that regulate dis...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549301/ https://www.ncbi.nlm.nih.gov/pubmed/26305326 http://dx.doi.org/10.1371/journal.pone.0136636 |