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Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer

Lung cancer or pulmonary carcinoma is primarily derived from epithelial cells that are thin and line on the alveolar surfaces of the lung for gas exchange. ANO1/TMEM16A, initially identified from airway epithelial cells, is a member of Ca(2+)-activated Cl(-) channels (CaCCs) that function to regulat...

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Detalles Bibliográficos
Autores principales: Jia, Linghan, Liu, Wen, Guan, Lizhao, Lu, Min, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549304/
https://www.ncbi.nlm.nih.gov/pubmed/26305547
http://dx.doi.org/10.1371/journal.pone.0136584