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Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor

Histone deacetylases (HDACs) act as corepressors in gene transcription by altering the acetylation of histones, resulting in epigenetic gene silencing. We previously reported that HDAC3 acts as a coactivator of the mineralocorticoid receptor (MR). Although HDAC3 forms complexes with class II HDACs,...

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Detalles Bibliográficos
Autores principales: Lee, Hae-Ahm, Song, Min-Ji, Seok, Young-Mi, Kang, Seol-Hee, Kim, Sang-Yeob, Kim, Inkyeom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549324/
https://www.ncbi.nlm.nih.gov/pubmed/26305553
http://dx.doi.org/10.1371/journal.pone.0136801