Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy

BACKGROUND: Synucleinopathy is any of a group of age-related neurodegenerative disorders including Parkinson's disease, multiple system atrophy, and dementia with Lewy Bodies, which is characterized by α-synuclein inclusions and parkinsonian motor deficits affecting millions of patients worldwi...

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Detalles Bibliográficos
Autores principales: Bai, Xiang, Wey, Margaret Chia-Ying, Fernandez, Elizabeth, Hart, Matthew J., Gelfond, Jonathan, Bokov, Alex F., Rani, Sheela, Strong, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549373/
https://www.ncbi.nlm.nih.gov/pubmed/26306821
http://dx.doi.org/10.3402/pba.v5.28743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549373/
https://www.ncbi.nlm.nih.gov/pubmed/26306821
http://dx.doi.org/10.3402/pba.v5.28743

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