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Preclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and Validation

Over the past 35 years, cure rates for pediatric cancers have increased dramatically. However, it is clear that further dose intensification using cytotoxic agents or radiation therapy is not possible without enhancing morbidity and long-term effects. Consequently, novel, less genotoxic, agents are...

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Detalles Bibliográficos
Autores principales: Geier, Brian, Kurmashev, Dias, Kurmasheva, Raushan T., Houghton, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549564/
https://www.ncbi.nlm.nih.gov/pubmed/26380223
http://dx.doi.org/10.3389/fonc.2015.00193