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Engineering catechol 1, 2-dioxygenase by design for improving the performance of the cis, cis-muconic acid synthetic pathway in Escherichia coli

Regulating and ameliorating enzyme expression and activity greatly affects the performance of a given synthetic pathway. In this study, a new synthetic pathway for cis, cis-muconic acid (ccMA) production was reconstructed without exogenous induction by regulating the constitutive expression of the i...

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Detalles Bibliográficos
Autores principales: Han, Li, Liu, Pi, Sun, Jixue, Wu, Yuanqing, Zhang, Yuanyuan, Chen, Wujiu, Lin, Jianping, Wang, Qinhong, Ma, Yanhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549619/
https://www.ncbi.nlm.nih.gov/pubmed/26306712
http://dx.doi.org/10.1038/srep13435