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The exosome controls alternative splicing by mediating the gene expression and assembly of the spliceosome complex

The exosome is a complex with exoribonuclease activity that regulates RNA surveillance and turnover. The exosome also plays a role in regulating the degradation of precursor mRNAs to maintain the expression of splicing variants. In Neurospora, the silencing of rrp44, which encodes the catalytic subu...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Wan, Yufeng, Huang, Guobin, Wang, Dongni, Yu, Xinyang, Huang, Guocun, Guo, Jinhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549623/
https://www.ncbi.nlm.nih.gov/pubmed/26306464
http://dx.doi.org/10.1038/srep13403