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An in silico Approach Reveals Associations between Genetic and Epigenetic Factors within Regulatory Elements in B Cells from Primary Sjögren’s Syndrome Patients

Recent advances in genetics have highlighted several regions and candidate genes associated with primary Sjögren’s syndrome (SS), a systemic autoimmune epithelitis that combines exocrine gland dysfunctions, and focal lymphocytic infiltrations. In addition to genetic factors, it is now clear that epi...

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Detalles Bibliográficos
Autores principales: Konsta, Orsia D., Le Dantec, Christelle, Charras, Amandine, Brooks, Wesley H., Arleevskaya, Marina I., Bordron, Anne, Renaudineau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549647/
https://www.ncbi.nlm.nih.gov/pubmed/26379672
http://dx.doi.org/10.3389/fimmu.2015.00437