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Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A

Small RhoGTPases, such as Cdc42 and RhoA, are key players in integrating external cues and intracellular signaling pathways that regulate growth cone (GC) motility. Indeed, Cdc42 is involved in actin polymerization and filopodia formation, whereas RhoA induces GC collapse and neurite retraction thro...

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Detalles Bibliográficos
Autores principales: Iseppon, Federico, Napolitano, Luisa M. R., Torre, Vincent, Cojoc, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549648/
https://www.ncbi.nlm.nih.gov/pubmed/26379503
http://dx.doi.org/10.3389/fncel.2015.00333