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Nanomicelle formulation for topical delivery of cyclosporine A into the cornea: in vitro mechanism and in vivo permeation evaluation

A stable topical ophthalmic cyclosporine A (CsA) formulation with good tolerance and high efficacy is still a desire in pharmaceutics and clinics. This article describes the preparation of CsA containing nanomicelles using a polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (PVCL-PVA-PEG)...

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Detalles Bibliográficos
Autores principales: Guo, Chuanlong, Zhang, Yan, Yang, Zhao, Li, Mengshuang, Li, Fengjie, Cui, Fenghua, Liu, Ting, Shi, Weiyun, Wu, Xianggen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549686/
http://dx.doi.org/10.1038/srep12968