Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design

Neuraminidase (NA) inhibitors are the dominant antiviral drugs for treating influenza in the clinic. Increasing prevalence of drug resistance makes the discovery of new NA inhibitors a high priority. Thirty-one triterpenoids from the medicinal mushroom Ganoderma lingzhi were analyzed in an in vitro...

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Detalles Bibliográficos
Autores principales: Zhu, Qinchang, Bang, Tran Hai, Ohnuki, Koichiro, Sawai, Takashi, Sawai, Ken, Shimizu, Kuniyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549708/
https://www.ncbi.nlm.nih.gov/pubmed/26307417
http://dx.doi.org/10.1038/srep13194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549708/
https://www.ncbi.nlm.nih.gov/pubmed/26307417
http://dx.doi.org/10.1038/srep13194

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