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Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells

Citreoviridin (CIT) is a mycotoxin derived from fungal species in moldy cereals. In our previous study, we reported that CIT stimulated autophagosome formation in human liver HepG2 cells. Here, we aimed to explore the relationship of autophagy with lysosomal membrane permeabilization and apoptosis i...

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Detalles Bibliográficos
Autores principales: Wang, Yuexia, Liu, Yanan, Liu, Xiaofang, Jiang, Liping, Yang, Guang, Sun, Xiance, Geng, Chengyan, Li, Qiujuan, Yao, Xiaofeng, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549738/
https://www.ncbi.nlm.nih.gov/pubmed/26258792
http://dx.doi.org/10.3390/toxins7083030