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Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington's Disease

Weight loss is an important complication of Huntington’s disease (HD), however the mechanism for weight loss in HD is not entirely understood. Mutant huntingtin is expressed in the gastrointestinal (GI) tract and, in HD mice, mutant huntingtin inclusions are found within the enteric nervous system a...

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Detalles Bibliográficos
Autores principales: McCourt, Andrew C, O'Donovan, Kirsty L, Ekblad, Eva, Sand, Elin, Craufurd, David, Rosser, Anne, Sanders, David, Stoy, Nicholas, Rickards, Hugh, Wierup, Nils, Bates, Gillian P., Björkqvist, Maria, Quarrell, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549855/
https://www.ncbi.nlm.nih.gov/pubmed/26581667
http://dx.doi.org/10.1371/currents.hd.858b4cc7f235df068387e9c20c436a79