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Calreticulin down-regulation inhibits the cell growth, invasion and cell cycle progression of human hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most frequent cancers in the world. Calreticulin(CRT) is aberrantly overexpressed in many human cancer cells. The function of CRT in HCC cells remains unclear. We attempted to investigate the effects and the underlying mechanisms of CRT down-r...

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Detalles Bibliográficos
Autores principales: Feng, Ruo, Ye, Jianwen, Zhou, Chuang, Qi, Lei, Fu, Zhe, Yan, Bing, Liang, Zhiwei, Li, Renfeng, Zhai, Wenlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549864/
https://www.ncbi.nlm.nih.gov/pubmed/26307067
http://dx.doi.org/10.1186/s13000-015-0382-1