Cargando…
Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing
BACKGROUND: The ability to modify the genome of any cell at a precise location has drastically improved with the recent discovery and implementation of CRISPR/Cas9 editing technology. However, the capacity to introduce specific directed changes at given loci is hampered by the fact that the major ce...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550049/ https://www.ncbi.nlm.nih.gov/pubmed/26307031 http://dx.doi.org/10.1186/s13073-015-0215-6 |