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Genomic analysis of codon usage shows influence of mutation pressure, natural selection, and host features on Marburg virus evolution

BACKGROUND: The Marburg virus (MARV) has a negative-sense single-stranded RNA genome, belongs to the family Filoviridae, and is responsible for several outbreaks of highly fatal hemorrhagic fever. Codon usage patterns of viruses reflect a series of evolutionary changes that enable viruses to shape t...

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Detalles Bibliográficos
Autores principales: Nasrullah, Izza, Butt, Azeem M, Tahir, Shifa, Idrees, Muhammad, Tong, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550055/
https://www.ncbi.nlm.nih.gov/pubmed/26306510
http://dx.doi.org/10.1186/s12862-015-0456-4