Over-expressing Akt in T cells to resist tumor immunosuppression and increase anti-tumor activity

BACKGROUND: Tumor employs various means to escape immunosurveillance and inhibit immune attack, and strategies have been developed to counteract the inhibitory signals. However, due to the complex suppressive mechanisms in the tumor microenvironment, blocking one or a few inhibitory signals has only...

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Detalles Bibliográficos
Autores principales: Wu, Yanhong, Deng, Zhenling, Tang, Yishu, Zhang, Shuren, Zhang, Yu-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550078/
https://www.ncbi.nlm.nih.gov/pubmed/26310246
http://dx.doi.org/10.1186/s12885-015-1611-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550078/
https://www.ncbi.nlm.nih.gov/pubmed/26310246
http://dx.doi.org/10.1186/s12885-015-1611-4

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