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Over-expressing Akt in T cells to resist tumor immunosuppression and increase anti-tumor activity
BACKGROUND: Tumor employs various means to escape immunosurveillance and inhibit immune attack, and strategies have been developed to counteract the inhibitory signals. However, due to the complex suppressive mechanisms in the tumor microenvironment, blocking one or a few inhibitory signals has only...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550078/ https://www.ncbi.nlm.nih.gov/pubmed/26310246 http://dx.doi.org/10.1186/s12885-015-1611-4 |