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Epothilones in epithelial ovarian, fallopian tube, or primary peritoneal cancer: a systematic review

Ovarian cancer is the most lethal gynecologic malignancy; consequently, there is a need for effective therapies. Epothilones are microtubule-stabilizing agents that inhibit cell growth. Currently, patupilone and its four synthetic derivatives ixabepilone, BMS-310705, sagopilone, 20-desmethyl-20-meth...

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Detalles Bibliográficos
Autores principales: Zagouri, Flora, Sergentanis, Theodoros N, Chrysikos, Dimosthenis, Dimopoulos, Meletios-Athanassios, Bamias, Aristotle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550178/
https://www.ncbi.nlm.nih.gov/pubmed/26316786
http://dx.doi.org/10.2147/OTT.S77342