Nrf2 and HSF-1 Pathway Activation via Hydroquinone-Based Proelectrophilic Small Molecules Is Regulated by Electrochemical Oxidation Potential

Activation of the Kelch-like ECH-associated protein 1/nuclear factor (erythroid-derived 2)-like 2 and heat-shock protein 90/heat-shock factor-1 signal-transduction pathways plays a central role in combatting cellular oxidative damage and related endoplasmic reticulum stress. Electrophilic compounds...

Descripción completa

Detalles Bibliográficos
Autores principales: Satoh, Takumi, Stalder, Romain, McKercher, Scott R., Williamson, Robert E., Roth, Gregory P., Lipton, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550314/
https://www.ncbi.nlm.nih.gov/pubmed/26243592
http://dx.doi.org/10.1177/1759091415593294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550314/
https://www.ncbi.nlm.nih.gov/pubmed/26243592
http://dx.doi.org/10.1177/1759091415593294

Ejemplares similares