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Identifying the Critical Domain of LL-37 Involved in Mediating Neutrophil Activation in the Presence of Influenza Virus: Functional and Structural Analysis

The human cathelicidin LL-37 has been shown to play a role in host defense against influenza A viruses (IAV) through direct antiviral effects and through modulating inflammatory responses to infection. We recently showed that LL-37 increases neutrophil respiratory burst and neutrophil extracellular...

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Detalles Bibliográficos
Autores principales: Tripathi, Shweta, Wang, Guangshun, White, Mitchell, Rynkiewicz, Michael, Seaton, Barbara, Hartshorn, Kevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550355/
https://www.ncbi.nlm.nih.gov/pubmed/26308522
http://dx.doi.org/10.1371/journal.pone.0133454