The Prostaglandin E2 Receptor EP4 Regulates Obesity-Related Inflammation and Insulin Sensitivity

With increasing body weight, macrophages accumulate in adipose tissue. There, activated macrophages secrete numerous proinflammatory cytokines and chemokines, giving rise to chronic inflammation and insulin resistance. Prostaglandin E(2) suppresses macrophage activation via EP4; however, the role of...

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Detalles Bibliográficos
Autores principales: Yasui, Mika, Tamura, Yukinori, Minami, Manabu, Higuchi, Sei, Fujikawa, Risako, Ikedo, Taichi, Nagata, Manabu, Arai, Hidenori, Murayama, Toshinori, Yokode, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550358/
https://www.ncbi.nlm.nih.gov/pubmed/26308623
http://dx.doi.org/10.1371/journal.pone.0136304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550358/
https://www.ncbi.nlm.nih.gov/pubmed/26308623
http://dx.doi.org/10.1371/journal.pone.0136304

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