A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells

Temozolomide (TMZ) is an oral alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma (GBM). Despite that high TMZ potential, progression of disease and recurrence are still observed. Therefore a better understanding of the mechanism of action of this drug is neces...

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Detalles Bibliográficos
Autores principales: Barciszewska, Anna-Maria, Gurda, Dorota, Głodowicz, Paweł, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550362/
https://www.ncbi.nlm.nih.gov/pubmed/26309255
http://dx.doi.org/10.1371/journal.pone.0136669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550362/
https://www.ncbi.nlm.nih.gov/pubmed/26309255
http://dx.doi.org/10.1371/journal.pone.0136669

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