Cargando…

Highly and Broad-Spectrum In Vitro Antitumor Active cis-Dichloridoplatinum(II) Complexes with 7-Azaindoles

The cis-[PtCl(2)(naza)(2)] complexes (1–3) containing monosubstituted 7-azaindole halogeno-derivatives (naza), showed significantly higher activity than cisplatin towards ovarian carcinoma A2780, its cisplatin-resistant variant A2780R, osteosarcoma HOS, breast carcinoma MCF7 and cervix carcinoma HeL...

Descripción completa

Detalles Bibliográficos
Autores principales: Štarha, Pavel, Dvořák, Zdeněk, Trávníček, Zdeněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550364/
https://www.ncbi.nlm.nih.gov/pubmed/26309251
http://dx.doi.org/10.1371/journal.pone.0136338