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A Fluorescent Probe to Measure DNA Damage and Repair

DNA damage and repair is a fundamental process that plays an important role in cancer treatment. Base excision repair (BER) is a major repair pathway that often leads to drug resistance in DNA-targeted cancer chemotherapy. In order to measure BER, we have developed a near infrared (NIR) fluorescent...

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Detalles Bibliográficos
Autores principales: Condie, Allison G., Yan, Yan, Gerson, Stanton L., Wang, Yanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550365/
https://www.ncbi.nlm.nih.gov/pubmed/26309022
http://dx.doi.org/10.1371/journal.pone.0131330