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Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA

The efflux transporter P-glycoprotein (P-gp) is an important mediator of various pharmacokinetic parameters, being expressed at numerous physiological barriers and also in multidrug-resistant cancer cells. Molecular cloning of homologous cDNAs is an important tool for the characterization of functio...

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Detalles Bibliográficos
Autores principales: Pluchino, Kristen M., Esposito, Dominic, Moen, Janna K., Hall, Matthew D., Madigan, James P., Shukla, Suneet, Procter, Lauren V., Wall, Vanessa E., Schneider, Thomas D., Pringle, Ian, Ambudkar, Suresh V., Gill, Deborah R., Hyde, Steven C., Gottesman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550409/
https://www.ncbi.nlm.nih.gov/pubmed/26309032
http://dx.doi.org/10.1371/journal.pone.0136396