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Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin

RNA-binding protein Musashi-2 (Msi2) is known to play a critical role in leukemogenesis and contributes to poor clinical prognosis in acute myeloid leukemia (AML). However, the effect of Msi2 silencing on treatment for AML still remains poorly understood. In this study, we used lentivirus-mediated R...

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Detalles Bibliográficos
Autores principales: Han, Yixiang, Ye, Aifang, Zhang, Yan, Cai, Zhimin, Wang, Wei, Sun, Lan, Jiang, Songfu, Wu, Jianbo, Yu, Kang, Zhang, Shenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550418/
https://www.ncbi.nlm.nih.gov/pubmed/26308531
http://dx.doi.org/10.1371/journal.pone.0136484