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The c.503T>C Polymorphism in the Human KLRB1 Gene Alters Ligand Binding and Inhibitory Potential of CD161 Molecules

Studying genetic diversity of immunologically relevant molecules can improve our knowledge on their functional spectrum in normal immune responses and may also uncover a possible role of different variants in diseases. We characterized the c.503T>C polymorphism in the human KLRB1 gene (Killer cel...

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Detalles Bibliográficos
Autores principales: Rother, Sascha, Hundrieser, Joachim, Pokoyski, Claudia, Kollrich, Sonja, Borns, Katja, Blasczyk, Rainer, Poehnert, Daniel, Klempnauer, Jürgen, Schwinzer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550425/
https://www.ncbi.nlm.nih.gov/pubmed/26309225
http://dx.doi.org/10.1371/journal.pone.0135682