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The c.503T>C Polymorphism in the Human KLRB1 Gene Alters Ligand Binding and Inhibitory Potential of CD161 Molecules
Studying genetic diversity of immunologically relevant molecules can improve our knowledge on their functional spectrum in normal immune responses and may also uncover a possible role of different variants in diseases. We characterized the c.503T>C polymorphism in the human KLRB1 gene (Killer cel...
Autores principales: | Rother, Sascha, Hundrieser, Joachim, Pokoyski, Claudia, Kollrich, Sonja, Borns, Katja, Blasczyk, Rainer, Poehnert, Daniel, Klempnauer, Jürgen, Schwinzer, Reinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550425/ https://www.ncbi.nlm.nih.gov/pubmed/26309225 http://dx.doi.org/10.1371/journal.pone.0135682 |
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