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Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation

Accumulating evidence supports the idea that secondary metabolites obtained from medicinal plants (phytometabolites) may be important contributors in the development of new chemotherapeutic agents to reduce the occurrence or recurrence of cancer. Our study focused on Dehydroleucodine (DhL), a sesqui...

Полное описание

Библиографические подробности
Главные авторы: Bailon-Moscoso, Natalia, González-Arévalo, Gabriela, Velásquez-Rojas, Gabriela, Malagon, Omar, Vidari, Giovanni, Zentella-Dehesa, Alejandro, Ratovitski, Edward A., Ostrosky-Wegman, Patricia
Формат: Online Статья Текст
Язык:English
Опубликовано: Public Library of Science 2015
Предметы:
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550445/
https://www.ncbi.nlm.nih.gov/pubmed/26309132
http://dx.doi.org/10.1371/journal.pone.0136527