RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13

Raf Kinase Inhibitory Protein or RKIP was initially identified as a Raf-1 binding protein using the yeast 2-hybrid screen. RKIP inhibits the activation phosphorylation of MEK by Raf-1 by competitively inhibiting the binding of MEK to Raf-1 and thus exerting an inhibitory effect on the Raf-MEK-Erk pa...

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Detalles Bibliográficos
Autores principales: Datar, Ila, Feng, Jingwei, Qiu, Xiaoliang, Lewandowski, John, Yeung, Miranda, Ren, Gang, Aras, Shweta, Al-Mulla, Fahd, Cui, Hongjuan, Trumbly, Robert, Arudra, Sri Krishna Chaitanya, De Las Casas, Luis E., de la Serna, Ivana, Bitar, Milad S., Yeung, Kam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550449/
https://www.ncbi.nlm.nih.gov/pubmed/26308852
http://dx.doi.org/10.1371/journal.pone.0134494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550449/
https://www.ncbi.nlm.nih.gov/pubmed/26308852
http://dx.doi.org/10.1371/journal.pone.0134494

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