Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei

The filamentous fungus Trichoderma reesei has tremendous capability to secrete proteins. Therefore, it would be an excellent host for producing high levels of therapeutic proteins at low cost. Developing a filamentous fungus to produce sensitive therapeutic proteins requires that protease secretion...

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Detalles Bibliográficos
Autores principales: Landowski, Christopher P., Huuskonen, Anne, Wahl, Ramon, Westerholm-Parvinen, Ann, Kanerva, Anne, Hänninen, Anna-Liisa, Salovuori, Noora, Penttilä, Merja, Natunen, Jari, Ostermeier, Christian, Helk, Bernhard, Saarinen, Juhani, Saloheimo, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550459/
https://www.ncbi.nlm.nih.gov/pubmed/26309247
http://dx.doi.org/10.1371/journal.pone.0134723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550459/
https://www.ncbi.nlm.nih.gov/pubmed/26309247
http://dx.doi.org/10.1371/journal.pone.0134723

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