Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact

Deciphering the multitude of epigenomic and genomic factors that influence the mutation rate is an area of great interest in modern biology. Recently, chromatin has been shown to play a part in this process. To elucidate this relationship further, we integrated our own ultra-deep sequenced human nuc...

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Detalles Bibliográficos
Autores principales: Yazdi, Puya G., Pedersen, Brian A., Taylor, Jared F., Khattab, Omar S., Chen, Yu-Han, Chen, Yumay, Jacobsen, Steven E., Wang, Ping H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550472/
https://www.ncbi.nlm.nih.gov/pubmed/26308346
http://dx.doi.org/10.1371/journal.pone.0136574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550472/
https://www.ncbi.nlm.nih.gov/pubmed/26308346
http://dx.doi.org/10.1371/journal.pone.0136574

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