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Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact
Deciphering the multitude of epigenomic and genomic factors that influence the mutation rate is an area of great interest in modern biology. Recently, chromatin has been shown to play a part in this process. To elucidate this relationship further, we integrated our own ultra-deep sequenced human nuc...
Autores principales: | Yazdi, Puya G., Pedersen, Brian A., Taylor, Jared F., Khattab, Omar S., Chen, Yu-Han, Chen, Yumay, Jacobsen, Steven E., Wang, Ping H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550472/ https://www.ncbi.nlm.nih.gov/pubmed/26308346 http://dx.doi.org/10.1371/journal.pone.0136574 |
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