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In vitro and in vivo growth alter the population dynamic and properties of a Jeryl Lynn mumps vaccine

Mumps vaccines are live attenuated viruses. They are known to vary in effectiveness, degree of attenuation and adverse event profile. However, the underlying reasons are poorly understood. We studied two closely related mumps vaccines which originate from the same attenuated Jeryl Lynn-5 strain but...

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Detalles Bibliográficos
Autores principales: Connaughton, Sarah M., Wheeler, Jun X., Vitková, Eva, Minor, Philip, Schepelmann, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550476/
https://www.ncbi.nlm.nih.gov/pubmed/26187256
http://dx.doi.org/10.1016/j.vaccine.2015.06.109