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Single Nucleotide Polymorphisms (SNPs) of RAD51-G172T and XRCC2-41657C/T Homologous Recombination Repair Genes and the Risk of Triple- Negative Breast Cancer in Polish Women

Double strand DNA breaks are the most dangerous DNA damage which, if non-repaired or misrepaired, may result in genomic instability, cancer transformation or cell death. RAD51 and XRCC2 encode proteins that are important for the repair of double-strand DNA breaks by homologous recombination. Therefo...

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Detalles Bibliográficos
Autores principales: Michalska, Magdalena M., Samulak, Dariusz, Romanowicz, Hanna, Smolarz, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550649/
https://www.ncbi.nlm.nih.gov/pubmed/25743260
http://dx.doi.org/10.1007/s12253-015-9922-y