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Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques

Nine million cases of tuberculosis (TB) were reported in 2013, with a further 1.5 million deaths attributed to the disease. When delivered as an intradermal (i.d.) injection, the Mycobacterium bovis BCG vaccine provides limited protection, whereas aerosol delivery has been shown to enhance efficacy...

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Detalles Bibliográficos
Autores principales: White, A. D., Sarfas, C., West, K., Sibley, L. S., Wareham, A. S., Clark, S., Dennis, M. J., Williams, A., Marsh, P. D., Sharpe, S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550663/
https://www.ncbi.nlm.nih.gov/pubmed/26108288
http://dx.doi.org/10.1128/CVI.00289-15