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Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques
Nine million cases of tuberculosis (TB) were reported in 2013, with a further 1.5 million deaths attributed to the disease. When delivered as an intradermal (i.d.) injection, the Mycobacterium bovis BCG vaccine provides limited protection, whereas aerosol delivery has been shown to enhance efficacy...
Autores principales: | White, A. D., Sarfas, C., West, K., Sibley, L. S., Wareham, A. S., Clark, S., Dennis, M. J., Williams, A., Marsh, P. D., Sharpe, S. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550663/ https://www.ncbi.nlm.nih.gov/pubmed/26108288 http://dx.doi.org/10.1128/CVI.00289-15 |
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