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Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

The macrophage response to planktonic Staphylococcus aureus involves the induction of proinflammatory microbicidal activity. However, S. aureus biofilms can interfere with these responses in part by polarizing macrophages toward an anti-inflammatory profibrotic phenotype. Here we demonstrate that co...

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Detalles Bibliográficos
Autores principales: Scherr, Tyler D., Hanke, Mark L., Huang, Ouwen, James, David B. A., Horswill, Alexander R., Bayles, Kenneth W., Fey, Paul D., Torres, Victor J., Kielian, Tammy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550693/
https://www.ncbi.nlm.nih.gov/pubmed/26307164
http://dx.doi.org/10.1128/mBio.01021-15