Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia

Medulloblastoma, the most common malignant brain tumor in children, occurs with increased frequency in individuals with Fanconi anemia who have biallelic germline mutations in BRCA2. We describe an 8-year-old child who had disseminated anaplastic medulloblastoma and a deleterious heterozygous BRCA2...

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Detalles Bibliográficos
Autores principales: Xu, Jingying, Margol, Ashley Sloane, Shukla, Anju, Ren, Xiuhai, Finlay, Jonathan L., Krieger, Mark D., Gilles, Floyd H., Couch, Fergus J., Aziz, Meraj, Fung, Eric T., Asgharzadeh, Shahab, Barrett, Michael T., Erdreich-Epstein, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550790/
https://www.ncbi.nlm.nih.gov/pubmed/26380221
http://dx.doi.org/10.3389/fonc.2015.00191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550790/
https://www.ncbi.nlm.nih.gov/pubmed/26380221
http://dx.doi.org/10.3389/fonc.2015.00191

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