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Prolactin and growth hormone affect metaphase-II chromosomes in aging oocytes via cumulus cells using similar signaling pathways

General senescence of the adult organism is closely connected with reproductive one. Meanwhile, the age-related reduction in the female fertility is primarily associated with a decline in the gamete quality. Molecular and cellular changes in oocytes of old mammalian females are very similar to those...

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Detalles Bibliográficos
Autores principales: Lebedeva, Irina Y., Singina, Galina N., Lopukhov, Alexander V., Shedova, Ekaterina N., Zinovieva, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550791/
https://www.ncbi.nlm.nih.gov/pubmed/26379702
http://dx.doi.org/10.3389/fgene.2015.00274