The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7

Castration-resistant (CR) prostate cancer (PCa) partly arises due to persistence of androgen receptor (AR) transcriptional activity in the absence of cognate ligand. An emerging mechanism underlying the CRPCa phenotype and predicting response to therapy is the expression of the constitutively-active...

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Detalles Bibliográficos
Autores principales: Stockley, Jacqueline, Markert, Elke, Zhou, Yan, Robson, Craig N., Elliott, David J., Lindberg, Johan, Leung, Hing Y., Rajan, Prabhakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550848/
https://www.ncbi.nlm.nih.gov/pubmed/26310125
http://dx.doi.org/10.1038/srep13426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550848/
https://www.ncbi.nlm.nih.gov/pubmed/26310125
http://dx.doi.org/10.1038/srep13426

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