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Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

A longstanding and still-increasing threat to the effective treatment of infectious diseases is resistance to antimicrobial countermeasures. Potentially, the targeting of host proteins and pathways essential for the detrimental effects of pathogens offers an approach that may discover broad-spectrum...

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Detalles Bibliográficos
Autores principales: Zilbermintz, Leeor, Leonardi, William, Jeong, Sun-Young, Sjodt, Megan, McComb, Ryan, Ho, Chi-Lee C., Retterer, Cary, Gharaibeh, Dima, Zamani, Rouzbeh, Soloveva, Veronica, Bavari, Sina, Levitin, Anastasia, West, Joel, Bradley, Kenneth A., Clubb, Robert T., Cohen, Stanley N., Gupta, Vivek, Martchenko, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550849/
https://www.ncbi.nlm.nih.gov/pubmed/26310922
http://dx.doi.org/10.1038/srep13476