Role of 5′TG3′-interacting factors (TGIFs) in Vorinostat (HDAC inhibitor)-mediated Corneal Fibrosis Inhibition

PURPOSE: We have previously reported that vorinostat, an FDA-approved, clinically used histone deacetylase (HDAC) inhibitor, attenuates corneal fibrosis in vivo in rabbits by blocking transforming growth factor β (TGFβ). The 5′TG3′-interacting factors (TGIFs) are transcriptional repressors of TGFβ1...

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Detalles Bibliográficos
Autores principales: Sharma, Ajay, Sinha, Nishant R., Siddiqui, Saad, Mohan, Rajiv R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551282/
https://www.ncbi.nlm.nih.gov/pubmed/26330748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551282/
https://www.ncbi.nlm.nih.gov/pubmed/26330748

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