Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

Cellular senescence is a widespread stress response and is widely considered to be an alternative cancer therapeutic goal. Unlike apoptosis, senescence is composed of a diverse set of subphenotypes, depending on which of its associated effector programs are engaged. Here we establish a simple and se...

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Detalles Bibliográficos
Autores principales: Sadaie, Mahito, Dillon, Christian, Narita, Masashi, Young, Andrew R. J., Cairney, Claire J., Godwin, Lauren S., Torrance, Christopher J., Bennett, Dorothy C., Keith, W. Nicol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551313/
https://www.ncbi.nlm.nih.gov/pubmed/26133385
http://dx.doi.org/10.1091/mbc.E15-01-0003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551313/
https://www.ncbi.nlm.nih.gov/pubmed/26133385
http://dx.doi.org/10.1091/mbc.E15-01-0003

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