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Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease

Metastatic breast cancer is usually diagnosed after becoming symptomatic, at which point it is rarely curable. Cell-free circulating tumor DNA (ctDNA) contains tumor-specific chromosomal rearrangements that may be interrogated in blood plasma. We evaluated serial monitoring of ctDNA for earlier dete...

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Detalles Bibliográficos
Autores principales: Olsson, Eleonor, Winter, Christof, George, Anthony, Chen, Yilun, Howlin, Jillian, Tang, Man-Hung Eric, Dahlgren, Malin, Schulz, Ralph, Grabau, Dorthe, van Westen, Danielle, Fernö, Mårten, Ingvar, Christian, Rose, Carsten, Bendahl, Pär-Ola, Rydén, Lisa, Borg, Åke, Gruvberger-Saal, Sofia K, Jernström, Helena, Saal, Lao H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551342/
https://www.ncbi.nlm.nih.gov/pubmed/25987569
http://dx.doi.org/10.15252/emmm.201404913