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Robust intestinal homeostasis relies on cellular plasticity in enteroblasts mediated by miR-8–Escargot switch

The intestinal epithelium is remarkably robust despite perturbations and demand uncertainty. Here, we investigate the basis of such robustness using novel tracing methods that allow simultaneously capturing the dynamics of stem and committed progenitor cells (called enteroblasts) and intestinal cell...

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Detalles Bibliográficos
Autores principales: Antonello, Zeus A, Reiff, Tobias, Ballesta-Illan, Esther, Dominguez, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551350/
https://www.ncbi.nlm.nih.gov/pubmed/26077448
http://dx.doi.org/10.15252/embj.201591517